BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○

Alpha-Ketoglutarate

A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)

356+ PubMed studies analyzed · 29 RCTs · Evidence Score: 46.1

Research Domains

Alpha-Ketoglutarate has been studied across 22 research domains including ⚡ Energy & Fatigue, 🫁 Liver & Detox, 🔬 Oncology, 🔬 Inflammation, ⏳ Longevity & Aging. The primary research focus is ⚡ Energy & Fatigue with 22% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Alpha-Ketoglutarate, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Glycine
2 shared targets
anemarrhena
2 shared targets
allium
2 shared targets
eupatorium
2 shared targets
gastrodia
2 shared targets
saposhnikovia
2 shared targets
taxillus
2 shared targets
Curcuma
2 shared targets
aucklandia
2 shared targets
cimicifuga
2 shared targets
Loading evidence profile...

This evidence profile for Alpha-Ketoglutarate is generated deterministically from 356 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.