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Alpha Ketoglutarate

A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)

354+ PubMed studies analyzed · 29 RCTs · Evidence Score: 46.2

Research Domains

Alpha Ketoglutarate has been studied across 22 research domains including ⚡ Energy & Fatigue, 🫁 Liver & Detox, 🔬 Oncology, 🔬 Inflammation, ⏳ Longevity & Aging. The primary research focus is ⚡ Energy & Fatigue with 22% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Alpha Ketoglutarate, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Glycine
2 shared targets
anemarrhena
2 shared targets
allium
2 shared targets
eupatorium
2 shared targets
gastrodia
2 shared targets
saposhnikovia
2 shared targets
taxillus
2 shared targets
Curcuma
2 shared targets
aucklandia
2 shared targets
cimicifuga
2 shared targets
Loading evidence profile...

This evidence profile for Alpha Ketoglutarate is generated deterministically from 354 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.