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Apolipoprotein C Iii

A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).

300+ PubMed studies analyzed · 15 RCTs · Evidence Score: 54.2

Research Domains

Apolipoprotein C Iii has been studied across 15 research domains including 🔥 Metabolic, ❤️ Cardiovascular, 🧠 Focus & Attention, 🫁 Liver & Detox, 🧬 Hormones. The primary research focus is 🔥 Metabolic with 40% of studies addressing this area.

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This evidence profile for Apolipoprotein C Iii is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.