How many studies have been conducted on Apolipoprotein E4?

BiohacksAI has indexed 300 PubMed studies on Apolipoprotein E4, including 5 randomized controlled trials (RCTs). 32% of studies involve human subjects.

What are the main research areas for Apolipoprotein E4?

The primary research domains for Apolipoprotein E4 are 🧠 Neuroprotection, 🧠 Cognitive, ⏳ Longevity & Aging. This is based on analysis of 300 PubMed studies using the BiohacksAI evidence platform.

BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.

Apolipoprotein E4

A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.

300+ PubMed studies analyzed · 5 RCTs · Evidence Score: 45.3

Research Domains

Apolipoprotein E4 has been studied across 20 research domains including 🧠 Neuroprotection, 🧠 Cognitive, ⏳ Longevity & Aging, 🧠 Memory, 🔥 Metabolic. The primary research focus is 🧠 Neuroprotection with 67% of studies addressing this area.

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This evidence profile for Apolipoprotein E4 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.