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Aromatase

An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.

300+ PubMed studies analyzed · 2 RCTs · Evidence Score: 43.9

Research Domains

Aromatase has been studied across 16 research domains including 🧬 Hormones, 🔬 Oncology, 💪 Strength & Power, ♀♂ Sexual Health, 🦴 Bone & Joint. The primary research focus is 🧬 Hormones with 44% of studies addressing this area.

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This evidence profile for Aromatase is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.