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Bradykinin

A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.

299+ PubMed studies analyzed · 5 RCTs · Evidence Score: 45.4

Research Domains

Bradykinin has been studied across 18 research domains including 🦴 Bone & Joint, 🔬 Inflammation, ❤️ Cardiovascular, 🫘 Kidney, 🫁 Respiratory. The primary research focus is 🦴 Bone & Joint with 17% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Bradykinin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Kallidin
2 shared targets
bufo
2 shared targets
anemarrhena
3 shared targets
gastrodia
3 shared targets
allium
3 shared targets
eupatorium
3 shared targets
dendrobium
2 shared targets
lycopus
2 shared targets
polygala
3 shared targets
belamcanda
3 shared targets
Loading evidence profile...

This evidence profile for Bradykinin is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.