A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN).
Butyrophilins has been studied across 12 research domains including 🛡️ Immunity, 🔬 Oncology, 🧠 Cognitive, 🔥 Metabolic, 🧬 Hormones. The primary research focus is 🛡️ Immunity with 58% of studies addressing this area.
This evidence profile for Butyrophilins is generated deterministically from 67 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.