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Calcineurin

A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes.

300+ PubMed studies analyzed · Evidence Score: 41.1

Research Domains

Calcineurin has been studied across 24 research domains including 🦴 Bone & Joint, 🏋️ Muscle & Hypertrophy, 🛡️ Immunity, 🔬 Oncology, 🫘 Kidney. The primary research focus is 🦴 Bone & Joint with 26% of studies addressing this area.

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This evidence profile for Calcineurin is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.