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Carbonic Anhydrase Ix

A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.

300+ PubMed studies analyzed · 2 RCTs · Evidence Score: 43.7

Research Domains

Carbonic Anhydrase Ix has been studied across 11 research domains including 🔬 Oncology, 🫘 Kidney, ⏳ Longevity & Aging, 🧠 Focus & Attention, 🫁 Liver & Detox. The primary research focus is 🔬 Oncology with 87% of studies addressing this area.

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This evidence profile for Carbonic Anhydrase Ix is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.