a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
Cardiac Glycosides has been studied across 15 research domains including ❤️ Cardiovascular, ⚡ Energy & Fatigue, 🔬 Oncology, 🦴 Bone & Joint, 🫘 Kidney. The primary research focus is ❤️ Cardiovascular with 17% of studies addressing this area.
This evidence profile for Cardiac Glycosides is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.