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Chenodeoxycholic Acid

A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

299+ PubMed studies analyzed · 9 RCTs · Evidence Score: 46.9

Research Domains

Chenodeoxycholic Acid has been studied across 11 research domains including 🫁 Liver & Detox, ❤️ Cardiovascular, 🔥 Metabolic, 🦠 Gut & Microbiome, 🧠 Focus & Attention. The primary research focus is 🫁 Liver & Detox with 34% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Chenodeoxycholic Acid, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Cholic
5 shared targets
Deoxycholic
4 shared targets
Glycochenodeoxycholic
4 shared targets
Taurochenodeoxycholic
4 shared targets
Dehydroepiandrosterone
7 shared targets
Dehydroepiandrosterone
7 shared targets
Ethanolamine
6 shared targets
Finasteride
7 shared targets
Loxapine
7 shared targets
Prasugrel
5 shared targets
Loading evidence profile...

This evidence profile for Chenodeoxycholic Acid is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.