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Cholesterol 7 Alpha Hydroxylase

A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.

300+ PubMed studies analyzed · 1 RCTs · Evidence Score: 45

Research Domains

Cholesterol 7 Alpha Hydroxylase has been studied across 12 research domains including ❤️ Cardiovascular, 🫁 Liver & Detox, 😴 Sleep, 🔥 Metabolic, 🧬 Hormones. The primary research focus is ❤️ Cardiovascular with 98% of studies addressing this area.

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This evidence profile for Cholesterol 7 Alpha Hydroxylase is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.