How many studies have been conducted on Cilastatin?

BiohacksAI has indexed 298 PubMed studies on Cilastatin, including 56 randomized controlled trials (RCTs). 62% of studies involve human subjects.

What are the main research areas for Cilastatin?

The primary research domains for Cilastatin are 🫘 Kidney, 🔬 Oncology, 🫁 Liver & Detox. This is based on analysis of 298 PubMed studies using the BiohacksAI evidence platform.

BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.

Cilastatin

A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.

298+ PubMed studies analyzed · 56 RCTs · Evidence Score: 52.9

Research Domains

Cilastatin has been studied across 14 research domains including 🫘 Kidney, 🔬 Oncology, 🫁 Liver & Detox, 🔬 Inflammation, 😴 Sleep. The primary research focus is 🫘 Kidney with 23% of studies addressing this area.

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This evidence profile for Cilastatin is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.