How many studies have been conducted on Complement C1s?

BiohacksAI has indexed 88 PubMed studies on Complement C1s, including 3 randomized controlled trials (RCTs). 35% of studies involve human subjects.

What are the main research areas for Complement C1s?

The primary research domains for Complement C1s are 🛡️ Immunity, 🔬 Oncology, 🦴 Bone & Joint. This is based on analysis of 88 PubMed studies using the BiohacksAI evidence platform.

Complement C1s

A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1 complex. Upon the binding of COMPLEMENT C1Q to antibodies, the activated COMPLEMENT C1R cleaves C1s into two chains, A (heavy) and B (light, the serine protease), linked by disulfide bonds yielding the active C1s. The activated C1s, in turn, cleaves COMPLEMENT C2 and COMPLEMENT C4 to form C4b2a (CLASSICAL C3 CONVERTASE).

88+ PubMed studies analyzed · 3 RCTs · Evidence Score: 48.3

Research Domains

Complement C1s has been studied across 15 research domains including 🛡️ Immunity, 🔬 Oncology, 🦴 Bone & Joint, 🫘 Kidney, ⏳ Longevity & Aging. The primary research focus is 🛡️ Immunity with 16% of studies addressing this area.

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This evidence profile for Complement C1s is generated deterministically from 88 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.