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Cortisone

A naturally occurring glucocorticoid that has been used in replacement therapy for ADRENAL INSUFFICIENCY and as an anti-inflammatory agent. Cortisone itself is inactive; it is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

299+ PubMed studies analyzed · Evidence Score: 39.2

Research Domains

Cortisone has been studied across 13 research domains including 🦴 Bone & Joint, 🫘 Kidney, 🫁 Respiratory, ✨ Skin & Hair, 👁️ Vision & Eye. The primary research focus is 🦴 Bone & Joint with 9% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Cortisone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Androstenedione
10 shared targets
17-alpha-Hydroxyprogesterone
9 shared targets
Prednisone
7 shared targets
Nandrolone
8 shared targets
Ethisterone
7 shared targets
Methyltestosterone
9 shared targets
stanolone
5 shared targets
Halcinonide
8 shared targets
Desoxycorticosterone
7 shared targets
Hydrocortisone
8 shared targets
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This evidence profile for Cortisone is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.