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Deoxyribonuclease I

An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.

299+ PubMed studies analyzed · 2 RCTs · Evidence Score: 45.2

Research Domains

Deoxyribonuclease I has been studied across 17 research domains including 🔬 Oncology, 🧠 Focus & Attention, ❤️ Cardiovascular, 🫁 Liver & Detox, 🦴 Bone & Joint. The primary research focus is 🔬 Oncology with 10% of studies addressing this area.

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This evidence profile for Deoxyribonuclease I is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.