A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS.
Deubiquitinating Enzyme Cyld has been studied across 11 research domains including 🔬 Oncology, 🛡️ Immunity, 🔬 Inflammation, ❤️ Cardiovascular, 🦴 Bone & Joint. The primary research focus is 🔬 Oncology with 46% of studies addressing this area.
This evidence profile for Deubiquitinating Enzyme Cyld is generated deterministically from 33 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.