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Dipeptidyl Peptidase 4

A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.

299+ PubMed studies analyzed · 5 RCTs · Evidence Score: 48.4

Research Domains

Dipeptidyl Peptidase 4 has been studied across 19 research domains including 🔥 Metabolic, ❤️ Cardiovascular, ✨ Skin & Hair, 🧬 Hormones, 🔬 Oncology. The primary research focus is 🔥 Metabolic with 62% of studies addressing this area.

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This evidence profile for Dipeptidyl Peptidase 4 is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.