A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.
Disintegrins has been studied across 15 research domains including 🔬 Oncology, 🦴 Bone & Joint, ✨ Skin & Hair, 🧠 Neuroprotection, ❤️ Cardiovascular. The primary research focus is 🔬 Oncology with 24% of studies addressing this area.
This evidence profile for Disintegrins is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.