A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.
Endosomal Sorting Complexes Required For Transport has been studied across 16 research domains including ⏳ Longevity & Aging, 🔬 Oncology, ⚡ Energy & Fatigue, 🔬 Inflammation, 🛡️ Immunity. The primary research focus is ⏳ Longevity & Aging with 17% of studies addressing this area.
This evidence profile for Endosomal Sorting Complexes Required For Transport is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.