A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Endothelin 1 has been studied across 21 research domains including ❤️ Cardiovascular, 🧠 Focus & Attention, 🦴 Bone & Joint, 🫁 Respiratory, 🫘 Kidney. The primary research focus is ❤️ Cardiovascular with 28% of studies addressing this area.
This evidence profile for Endothelin 1 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.