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Endothelin 3

A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It also is found throughout the gastrointestinal tract and in the lung and kidney. (N Eng J Med 1995;333(6):356-63)

300+ PubMed studies analyzed · Evidence Score: 46.2

Research Domains

Endothelin 3 has been studied across 20 research domains including ❤️ Cardiovascular, ✨ Skin & Hair, 🫘 Kidney, 🧠 Focus & Attention, 🦴 Bone & Joint. The primary research focus is ❤️ Cardiovascular with 14% of studies addressing this area.

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This evidence profile for Endothelin 3 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.