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Endothelins

The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.

300+ PubMed studies analyzed · Evidence Score: 44

Research Domains

Endothelins has been studied across 18 research domains including ❤️ Cardiovascular, 🫘 Kidney, 🦴 Bone & Joint, 🫁 Respiratory, 🔬 Oncology. The primary research focus is ❤️ Cardiovascular with 16% of studies addressing this area.

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This evidence profile for Endothelins is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.