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Flap Endonucleases

a DNA structure called a DNA flap. The DNA flap structure occurs in double-stranded DNA containing a single-stranded break where the 5' portion of the downstream strand is too long and overlaps the 3' end of the upstream strand. Flap endonucleases cleave the downstream strand of the overlap flap structure precisely after the first base-paired nucleotide, creating a ligatable nick.

36+ PubMed studies analyzed · Evidence Score: 38.2

Research Domains

Flap Endonucleases has been studied across 6 research domains including 🧠 Focus & Attention, 🦴 Bone & Joint, 🧠 Cognitive, 🔬 Inflammation, 🧘 Stress & Anxiety. The primary research focus is 🧠 Focus & Attention with 8% of studies addressing this area.

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This evidence profile for Flap Endonucleases is generated deterministically from 36 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.