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Ghrelin

A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.

299+ PubMed studies analyzed · 5 RCTs · Evidence Score: 47.6

Research Domains

Ghrelin has been studied across 21 research domains including 🔥 Metabolic, 🧬 Hormones, ⚡ Energy & Fatigue, 🔬 Oncology, 🦠 Gut & Microbiome. The primary research focus is 🔥 Metabolic with 25% of studies addressing this area.

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This evidence profile for Ghrelin is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.