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Granulins

the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc.

111+ PubMed studies analyzed · 1 RCTs · Evidence Score: 43.8

Research Domains

Granulins has been studied across 12 research domains including 🔬 Oncology, 🧠 Neuroprotection, 🫁 Liver & Detox, 🔬 Inflammation, 🛡️ Immunity. The primary research focus is 🔬 Oncology with 17% of studies addressing this area.

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This evidence profile for Granulins is generated deterministically from 111 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.