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Guanylyl Imidodiphosphate

A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.

300+ PubMed studies analyzed · Evidence Score: 41.6

Research Domains

Guanylyl Imidodiphosphate has been studied across 20 research domains including 🦴 Bone & Joint, 🧠 Focus & Attention, 🌤️ Mood & Depression, 🫘 Kidney, 🧬 Hormones. The primary research focus is 🦴 Bone & Joint with 14% of studies addressing this area.

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This evidence profile for Guanylyl Imidodiphosphate is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.