An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.
Heparin Binding Egf Like Growth Factor has been studied across 20 research domains including 🔬 Oncology, ✨ Skin & Hair, 🦠 Gut & Microbiome, 🧬 Hormones, 🔬 Inflammation. The primary research focus is 🔬 Oncology with 24% of studies addressing this area.
This evidence profile for Heparin Binding Egf Like Growth Factor is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.