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Histone Deacetylase 3

A histone deacetylase that catalyzes the deacetylation of the core HISTONES (H2A, H2B,H3, and H4) as well as other cellular proteins. It functions in the CELL NUCLEUS as part of the nuclear-receptor corepressor complex to regulate the GENETIC TRANSCRIPTION of NUCLEAR RECEPTORS.

300+ PubMed studies analyzed · Evidence Score: 42.9

Research Domains

Histone Deacetylase 3 has been studied across 21 research domains including 🔬 Oncology, 🔬 Inflammation, 🔥 Metabolic, ❤️ Cardiovascular, ⏳ Longevity & Aging. The primary research focus is 🔬 Oncology with 32% of studies addressing this area.

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This evidence profile for Histone Deacetylase 3 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.