Insulin

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).

1,000 PubMed studies analyzed · 268 RCTs · Evidence Score: 67

Research Domains

Insulin has been studied across 18 research domains including 🔥 Metabolic, 🧬 Hormones, ❤️ Cardiovascular, 😴 Sleep, 🫁 Liver & Detox. The primary research focus is 🔥 Metabolic with 85% of studies addressing this area.

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This evidence profile for Insulin is generated deterministically from 1,000 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.