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Interleukin 18

A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.

300+ PubMed studies analyzed · 2 RCTs · Evidence Score: 49.1

Research Domains

Interleukin 18 has been studied across 19 research domains including 🔬 Inflammation, 🛡️ Immunity, 🔬 Oncology, 🦴 Bone & Joint, ❤️ Cardiovascular. The primary research focus is 🔬 Inflammation with 98% of studies addressing this area.

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This evidence profile for Interleukin 18 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.