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Ivabradine

A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.

293+ PubMed studies analyzed · 16 RCTs · Evidence Score: 48.2

Research Domains

Ivabradine has been studied across 14 research domains including ❤️ Cardiovascular, 😴 Sleep, 🔬 Inflammation, 🧠 Focus & Attention, 🏋️ Muscle & Hypertrophy. The primary research focus is ❤️ Cardiovascular with 52% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Ivabradine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

sumanirole
2 shared targets
roxindole
2 shared targets
Dimethindene
3 shared targets
5
2 shared targets
Clonidine
3 shared targets
Penbutolol
2 shared targets
fauc
2 shared targets
ethopropazine
3 shared targets
Dihydroergocryptine
2 shared targets
mazapertine
2 shared targets
Loading evidence profile...

This evidence profile for Ivabradine is generated deterministically from 293 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.