A small leucine-rich proteoglycan that contains 10 tandem leucine repeats and four N-linked sites within the leucine repeat region that may be substituted with KERATAN SULFATE. These properties and its horseshoe shape allow it to mediate interactions among COLLAGEN molecules within fibrils. It is expressed in most mesenchymal tissues as well as the CORNEA, where it functions to maintain transparency.
Lumican has been studied across 17 research domains including 🔬 Oncology, ✨ Skin & Hair, 🦴 Bone & Joint, 🏋️ Muscle & Hypertrophy, ⏳ Longevity & Aging. The primary research focus is 🔬 Oncology with 31% of studies addressing this area.
This evidence profile for Lumican is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.