How many studies have been conducted on Mechanistic Target Of Rapamycin Complex 2?

BiohacksAI has indexed 96 PubMed studies on Mechanistic Target Of Rapamycin Complex 2. 12% of studies involve human subjects.

What are the main research areas for Mechanistic Target Of Rapamycin Complex 2?

The primary research domains for Mechanistic Target Of Rapamycin Complex 2 are 🏋️ Muscle & Hypertrophy, 🔬 Oncology, 🔥 Metabolic. This is based on analysis of 96 PubMed studies using the BiohacksAI evidence platform.

Mechanistic Target Of Rapamycin Complex 2

A multiprotein complex consisting of mTOR KINASE; MLST8 PROTEIN; rapamycin-insensitive companion of mTOR protein (RICTOR PROTEIN); and PRR5 (proline-rich protein 5). Like mTORC1, it also regulates cell growth and proliferation in response to growth factors but may not be as sensitive to nutrient availability and is insensitive to SIROLIMUS. In contrast to mTORC1, it can regulate the ACTIN CYTOSKELETON through RHO GTPASES to promote the formation of STRESS FIBERS. The mTORC2 complex also plays a critical role in AKT1 PROTEIN KINASE phosphorylation and activation.

96+ PubMed studies analyzed · Evidence Score: 41.1

Research Domains

Mechanistic Target Of Rapamycin Complex 2 has been studied across 23 research domains including 🏋️ Muscle & Hypertrophy, 🔬 Oncology, 🔥 Metabolic, ⏳ Longevity & Aging, 🧬 Hormones. The primary research focus is 🏋️ Muscle & Hypertrophy with 69% of studies addressing this area.

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This evidence profile for Mechanistic Target Of Rapamycin Complex 2 is generated deterministically from 96 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.