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Methimazole

A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.

295+ PubMed studies analyzed · 19 RCTs · Evidence Score: 44.5

Research Domains

Methimazole has been studied across 17 research domains including 🧬 Hormones, 🫁 Liver & Detox, 🔬 Inflammation, 🛡️ Immunity, ✨ Skin & Hair. The primary research focus is 🧬 Hormones with 72% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Methimazole, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Nialamide
4 shared targets
trolox
3 shared targets
lonidamine
4 shared targets
Oxymetholone
6 shared targets
Ascorbic
3 shared targets
Ascorbic
3 shared targets
Phenylbutazone
5 shared targets
iodoform
4 shared targets
Dimethisterone
4 shared targets
Penicillamine
2 shared targets
Loading evidence profile...

This evidence profile for Methimazole is generated deterministically from 295 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.