A developmentally regulated, HEPARIN-binding secreted growth factor homologous to pleiotrophin (PTN). It regulates cell proliferation through its interaction with ANAPLASTIC LYMPHOMA KINASE (ALK) and is involved in the formation of NEOINTIMA following arterial injury.
Midkine has been studied across 18 research domains including 🛡️ Immunity, 🔬 Inflammation, 🔬 Oncology, 🧠 Learning, 🫁 Liver & Detox. The primary research focus is 🛡️ Immunity with 57% of studies addressing this area.
This evidence profile for Midkine is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.