A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis.
Phosphodiesterase I has been studied across 14 research domains including 🫁 Liver & Detox, 🔬 Oncology, 🔥 Metabolic, 🧠 Focus & Attention, ❤️ Cardiovascular. The primary research focus is 🫁 Liver & Detox with 17% of studies addressing this area.
This evidence profile for Phosphodiesterase I is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.