A plant species in the PIPERACEAE plant family. It is a common spice on foods and is used medicinally to increase gastrointestinal assimilation of other supplements and drugs. Piperine is a key component. Black pepper is picked unripe and heaped for a few days to ferment. White Pepper is the ripe fruit dehulled by maceration in water.
Piper Nigrum has been studied across 15 research domains including 🔬 Inflammation, 🔬 Oncology, 🧠 Neuroprotection, 🔥 Metabolic, 🛡️ Immunity. The primary research focus is 🔬 Inflammation with 17% of studies addressing this area.
Known as hujiao / 胡椒 in Ayurveda. Virya (potency): Kidney, Spleen, Stomach. Rasa (taste): Pungent, Sweet. Karma (actions): Descends Qi, Warms the middle, Expels phlegm, Eliminates Wind-Cold from the Zang-Fu organs, Dispels Cold Qi from the stomach orifice, Resolves food stagnation, Reverses rebellious Qi in cholera, Regulates the five Zang organs, Strengthens Kidney Qi, Treats Cold dysentery, Detoxifies fish, meat, turtle, and mushroom poisons, Eliminates gastric Cold and water vomiting, Treats Cold-slippery Large Intestine, Warms the intestines and stomach, Eliminates Cold-Dampness.
The following compounds share molecular targets with Piper Nigrum, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Piper Nigrum is generated deterministically from 199 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.