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Pregnanediol

An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.

300+ PubMed studies analyzed · Evidence Score: 43.7

Research Domains

Pregnanediol has been studied across 12 research domains including 🧬 Hormones, 😴 Sleep, 🫘 Kidney, ♀♂ Sexual Health, 👁️ Vision & Eye. The primary research focus is 🧬 Hormones with 39% of studies addressing this area.

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This evidence profile for Pregnanediol is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.