BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Pregnenolone

A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

418+ PubMed studies analyzed · 31 RCTs · Evidence Score: 44.6

Research Domains

Pregnenolone has been studied across 24 research domains including 🧬 Hormones, 🫘 Kidney, ❤️ Cardiovascular, 💪 Strength & Power, 🧘 Stress & Anxiety. The primary research focus is 🧬 Hormones with 23% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Pregnenolone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Nandrolone
12 shared targets
Dehydroepiandrosterone
12 shared targets
Dehydroepiandrosterone
12 shared targets
Itraconazole
11 shared targets
Androstenedione
11 shared targets
Polidocanol
12 shared targets
Ethisterone
9 shared targets
Levonorgestrel
14 shared targets
Norgestrel
14 shared targets
Methandrostenolone
8 shared targets
Loading evidence profile...

This evidence profile for Pregnenolone is generated deterministically from 418 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.