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Pro Opiomelanocortin

A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).

300+ PubMed studies analyzed · Evidence Score: 44.7

Research Domains

Pro Opiomelanocortin has been studied across 22 research domains including 🔥 Metabolic, ✨ Skin & Hair, 🧬 Hormones, 🔬 Oncology, 🫘 Kidney. The primary research focus is 🔥 Metabolic with 16% of studies addressing this area.

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This evidence profile for Pro Opiomelanocortin is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.