A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
Proteasome Endopeptidase Complex has been studied across 15 research domains including ❤️ Cardiovascular, 🔬 Oncology, 🔬 Inflammation, 🛡️ Immunity, ⏳ Longevity & Aging. The primary research focus is ❤️ Cardiovascular with 21% of studies addressing this area.
This evidence profile for Proteasome Endopeptidase Complex is generated deterministically from 24 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.