A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
Pyrrolizidine Alkaloids has been studied across 6 research domains including 🫁 Liver & Detox, 🔬 Oncology, 🧠 Focus & Attention, 🔬 Inflammation, 🫘 Kidney. The primary research focus is 🫁 Liver & Detox with 18% of studies addressing this area.
This evidence profile for Pyrrolizidine Alkaloids is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.