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Pyrrolizidine Alkaloids

A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.

299+ PubMed studies analyzed · Evidence Score: 36.4

Research Domains

Pyrrolizidine Alkaloids has been studied across 6 research domains including 🫁 Liver & Detox, 🔬 Oncology, 🧠 Focus & Attention, 🔬 Inflammation, 🫘 Kidney. The primary research focus is 🫁 Liver & Detox with 18% of studies addressing this area.

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This evidence profile for Pyrrolizidine Alkaloids is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.