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Safrole

A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).

299+ PubMed studies analyzed · Evidence Score: 37.1

Research Domains

Safrole has been studied across 15 research domains including 🫁 Liver & Detox, 🔬 Oncology, 🔬 Inflammation, 🦴 Bone & Joint, 😴 Sleep. The primary research focus is 🫁 Liver & Detox with 25% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Safrole, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Levobupivacaine
2 shared targets
bdb
2 shared targets
bdb
2 shared targets
Phenacetin
2 shared targets
Methylcholanthrene
5 shared targets
diacerein
2 shared targets
bdb
2 shared targets
Carbimazole
2 shared targets
Mephenesin
2 shared targets
Lactic
2 shared targets
Loading evidence profile...

This evidence profile for Safrole is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.