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Semaphorin 3a

The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.

300+ PubMed studies analyzed · Evidence Score: 46.2

Research Domains

Semaphorin 3a has been studied across 22 research domains including 🔬 Oncology, 🦴 Bone & Joint, 🧠 Learning, 🫘 Kidney, 🔬 Inflammation. The primary research focus is 🔬 Oncology with 20% of studies addressing this area.

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This evidence profile for Semaphorin 3a is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.