A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
Sirtuin 1 has been studied across 26 research domains including ⏳ Longevity & Aging, 🔬 Oncology, 🔬 Inflammation, 🔥 Metabolic, 🧘 Stress & Anxiety. The primary research focus is ⏳ Longevity & Aging with 97% of studies addressing this area.
This evidence profile for Sirtuin 1 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.