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Sirtuin 2

A sirtuin family member found primarily in the CYTOPLASM. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.

300+ PubMed studies analyzed · Evidence Score: 42.9

Research Domains

Sirtuin 2 has been studied across 22 research domains including ⏳ Longevity & Aging, 🔬 Oncology, 🫁 Liver & Detox, 🔬 Inflammation, 🧠 Neuroprotection. The primary research focus is ⏳ Longevity & Aging with 89% of studies addressing this area.

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This evidence profile for Sirtuin 2 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.