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Sirtuin 3

A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.

300+ PubMed studies analyzed · Evidence Score: 42.9

Research Domains

Sirtuin 3 has been studied across 24 research domains including ⏳ Longevity & Aging, ⚡ Energy & Fatigue, 🔬 Inflammation, 🧘 Stress & Anxiety, 🔬 Oncology. The primary research focus is ⏳ Longevity & Aging with 93% of studies addressing this area.

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This evidence profile for Sirtuin 3 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.