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Smallpox Vaccine

A VACCINIA VIRUS vaccine used for immunization against SMALLPOX. It is now recommended only for laboratory workers exposed to SMALLPOX VIRUS. Certain countries continue to vaccinate those in the military service. Rare complications most often associated with older generation smallpox vaccines include VACCINIA, secondary bacterial infections, and ENCEPHALOMYELITIS. Because MONKEYPOX VIRUS and SMALLPOX VIRUS are both ORTHOPOXVIRUS and are closely related smallpox vaccines provide effective CROSS-PROTECTION against MPOX, MONKEYPOX (https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html).

298+ PubMed studies analyzed · 3 RCTs · Evidence Score: 42.2

Research Domains

Smallpox Vaccine has been studied across 7 research domains including 🛡️ Immunity, ✨ Skin & Hair, 🫘 Kidney, ♀♂ Sexual Health, ❤️ Cardiovascular. The primary research focus is 🛡️ Immunity with 41% of studies addressing this area.

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This evidence profile for Smallpox Vaccine is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.