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Sphingomyelin Phosphodiesterase

An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.

232+ PubMed studies analyzed · Evidence Score: 47.3

Research Domains

Sphingomyelin Phosphodiesterase has been studied across 21 research domains including 🔥 Metabolic, 🔬 Oncology, ⏳ Longevity & Aging, 🫁 Liver & Detox, 🫘 Kidney. The primary research focus is 🔥 Metabolic with 19% of studies addressing this area.

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This evidence profile for Sphingomyelin Phosphodiesterase is generated deterministically from 232 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.